Bacterial Drug Delivery Systems and nanoparticles

Drug delivery systems use different carrier cage-like structures such as bucky ball, therapeutic spheres, carbon nanotube spheres, tiny-tots, smart dots, paramagnetic nanoparticle cages, dendrimers, liposomes etc. The major developments are reported based on the physical properties of these particles such as paramagnetic, immunity, protein profile, transport dynamics, molecular recognition, receptor compatibility. In this approach drugs can be delivered efficiently at target and tracked in time-dependent manner for drug action at target with serial tissue changes by drug action. Several potential nanoparticles such as iron, zinc, cadmium, silver, gold, rhenium, gadolinium, lanthenum etc. have emerged as bioimaging contrast agents for MRI, radiography, optical, PET, SPECT imaging modalities. In principle, pH dependent delivery systems are designed based on the nanoparticle bound carrier as chemically visible complex by enzyme, chemiluminisence, antigenantibody, fluorescence, dye ratiometric reactions. Major developments are made in therapeutics in tumor, neuropathies, uropathies, cardiovascular diseases, blood and pancreas targeted therapies. Key word: drug delivery, nanoparticles, therapeutics,